Grape Seed Extract (GSE) is made from the seeds of grapes that have been dried and pulverized. Grape seeds are rich in antioxidants and are the best known source of proanthocyanidins (OPC's). By reducing oxidative stress, GSE can reduce tissue damage to your organs including the heart, liver, and kidneys*. It may improve circulation by reducing LDL levels*, and it may promote collagen formation and improve bone density*. Nano Grape Seed Extract has been nano particle-sized (1-100 nm in sized).